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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6442a6e433b04535d6e6aceba41ca1c99dba81defc86f2880501414b886b75b' 
  AND token = '+0Jlbdbn3Rf+CrRIivH6TRWqA/Y13r5LpDr3f+wUoTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}