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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e46ab1b0af1bfd4c6a3deed5f67f1e2b2c39fd34f8dfab13bc6302536abd66' 
  AND token = 'IYSTT6gqkL3FCDiCmuREHyNEBDfcgMjvo2NE1ziSDq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}