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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a746ab66071177b52078306bd506ca863ca8073fc4b7638cd0824c6611156c6' 
  AND token = '/0CZE2AieFWeuNyqpRSLiUSakmy7rVk9KKYfikZO5dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}