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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fdc98edd9d6657f93e91346e42eb373f17132ac1b4227d66f5bf4f6a3bf32a3' 
  AND token = 'jAkDaVxMsCEI27s+AYoSpSTpOMmLTDRbXqx96OqeZDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}