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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a51306dd35acf267030451369b136a416a6baa33e22fdd45adb8413a80eddb27' 
  AND token = 'GQ65Ln/tTj+I20qVIKFw4utpnxe9PO3DpvXKbWSv4bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}