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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493fcaf8035b8c98d43b34f4f0f1aecae5bf0aebf1da1646f83e25def2cb5d9c' 
  AND token = 'O3+zeQJVrd4xiyHIyk3PZJ6LOA5/ERTXJ3IPS6hyZYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}