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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '027ae65c8e0a965155aa05089e82a64dad691e7a884e9173bb65b76319fa0b66' 
  AND token = 'il2o79+nF10kPEr23lehGSy+xeK+oXuV1AQmq2hxVFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}