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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c147763a2f3f45cbe40e1c4e7a95aecffb3224da400bf63e37476e714d517cf5' 
  AND token = 'UO3gUU70lSvKFGXfCRYMtpipaGDoURSyRO516nd1bEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}