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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a843799409a7a439b7a78d061923e63d3903b321c97fb0927f4ba56e76a0c6d' 
  AND token = 'atuSCSoTJ4eUfd+pe4t5weXBngym4wp6d/9tb/A442g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}