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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3cf8b650723e86efa8bdf1aeea476a7ad672c131227710238339d7a226d04f' 
  AND token = 'qx65tQ3MJNnejXp1syvRnr9RKu0hS6wqB5v0WvgVTd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}