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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1128c5b0141bef1c0d7399bc13e1d4f51d747b309385ac9093af7972985dc1b' 
  AND token = 'CDkZRWRqZIZ0oGOyNKQ0IMeOSek3YLGG2POCUHg+4AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}