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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7b9b453c7327f58603000fbd0808a257e1fdf1bbfbecec3fb0c8d7265098155' 
  AND token = '/9u4Wzi8RL10SI7+2lyUaFeLw0Vm14jfVTv2a+EgTN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}