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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ebd06f0af26c43d682aafa2e57bf41f2b9b5a24fb9499a64ed89ef1cd29061' 
  AND token = 'tZXvRcnW2YUUM0S+Z1BOD87pxaltHuE0Y44lvSYBiJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}