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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161fc275f0c8d21811b31aeb07f4ca3baf7d05d464dc818a438d4744db157d76' 
  AND token = 'VlTS5KRgdiP0BG6rIG36YK1O5riDYvmO+/5q62xCmx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}