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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129cc4e4bea161c9e887568c53d94ff9d1c805f610010e16e963d5422bb29341' 
  AND token = 'uAafQ93KfxzwN7uRdC9QYV4sr+bWp5yULlBQqNzkRm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}