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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186053a369e94f05cd61c0ac2eeb38478ae2ead6705ddc62eb74877dee005f30' 
  AND token = 'pcc5UNYi8YkleIB7N1rLZzsh8dnYhGbbURpUM1FbVUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}