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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e414e3e3164bb257313dc69ebb84571a48ca297de3d14e605c59b2a02855af7' 
  AND token = 'R4xm80kM0wuPMCyVgt67hjf9WTrTs8LqbTCOdEIBKLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}