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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8450f894b9712f8dd255840ea981fbfbedc68405c220c12714bb970836747eda' 
  AND token = 'KXjAppFIWaM2pBR0GvNnLK5NkRej6BJSei3c87ONXFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}