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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1845c6f4c272893a6cadd8253c41b50e1dab950626d59e12b6ad9799d17cccf5' 
  AND token = 'jmM4JucvfgrZIStd4TJis0lB/yQz8C8Dkrvaz3Rg4Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}