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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15eefe3dcf4c8c5a1f667afa9c93043516519d7b8ff7c412e38ef7971807e3d4' 
  AND token = 'Udf93m9/sgiF92I6A1UM0jREjIm9wVvDPaRUYnvr2Qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}