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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a2cd65a33e427befa58ebf36efb9dc603f0a8f9e04d93bd44b15b04b14a023' 
  AND token = 'LCzDQUY3+EXHcLiy95Fh1AVkAjt595ITs93TdLxiB4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}