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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74c2f4d18f46b03eff87a6c338f1cc1760eb78b0d92a038c424d8a90074f48a4' 
  AND token = '5znManvJDwnmtuMZ0ri4rWG57b3lyqw580l8/exOgXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}