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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1086c6ecd79e85cf6fe2414f1f7d84c109e7b57b5a0c18e51e4889dd9fc8d43c' 
  AND token = 'EXqsYm4HNOCg4z5Do4GIbij0zi1IHWQx/GZPmCjIzHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}