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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeba8194a28a2d33966b0416d347177841b67b0440d9a1fdafc84532380ad887' 
  AND token = 'puwUqcTf+cdwkzVK0frmzUwSc+AnoU6cFvoTnVxisqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}