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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01516f9eda22adad1a8cc1167f287b76bfcf1091eb627a10547575b502c97ccd' 
  AND token = 'g7O9gE5S8sN/Cmsj7LsslB0s+6yUDWNtgOaxBfqwVaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}