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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec3a2c2249acc092d82400a98d90418508a30f9c6eae6cf6b5f88aaf8acae52c' 
  AND token = 'BbVFiQjgG2caFI5R7uIsogMrPqs86d3OuoN6q/e0Yj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}