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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f427be1f5cc1e08d9de99da5e17b732331caf6b14035ee234a105052ce84367' 
  AND token = '6NoVA8qrE2oZsKlvbredFnZqp7VPLmo9f9WbUb7EUvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}