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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4d42d8e2f336091b387e7c4b76312040ae2e33a62e4a0d498e4d07af9533d7' 
  AND token = 'IKaV+5FH5Nwe1zqqAck0KkkiPQjEP3UKeh+3sFpzlMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}