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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a3435fa52b2fab7a825e2804f0aa5fc65291fce44e972ce98159375e388cdf' 
  AND token = 'mEenOLZz9/LcaAqDQ89tT8fAO/aM96O3pPFzrYmjW3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}