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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cfaed7c7a8fe9c36db08d204c9687c0802b50e1d749c7c7e9adcceb6a7de52f' 
  AND token = '+rzWpmk6j3up7NEOl8sCDppLuAZtszJuor9vn4/ityU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}