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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91be41c32e16223782e7fbf740d9a64381430c748f179f57b929fee8a31f5c61' 
  AND token = '2l3a+oz9aAOBKqqagL0kjsT4tJwZ663zXbR3MFPcWXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}