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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2571f90937b950734ba2415919c81806e46f997a68d786d36eaf4b11b62b243' 
  AND token = 'I4ZFT1nsyzrRAQmonpf0Gz2GW7xriBu6MkWj6GVJXB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}