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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51157abaf1488d7d0a371e96d2aa12a0d9ae86074f8fd6f07c3faf73cb336c2a' 
  AND token = 'j1IQg/ekgZyS+W8PWa0m/gk4ay0CnR/lvo2sBefZBh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}