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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d59796e485fd28846e2cab5609bda0124c67fd8d20a5672cc5c0c97567f3034' 
  AND token = 'xzypPVL5d4s2o0P+rr9U2ovLEr00iunjXjOtWU7ECjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}