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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '791d74609c06e03505b4e8e280d33f2c686815b57c30799d2fed5769aab850a6' 
  AND token = 'a2xDxjxYqGdsZ3mxnfxskWmyw3tfsI8c2dm+epD0e/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}