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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b92ddc0e681603d516b3e485bd2d09a9ba05de98cc78ffb444d972b2a4a7cb0' 
  AND token = '8r7Qm7ZeMrN7UUSMpojLrhUCTepccJ21tEv+d+Uhw4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}