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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70f2a886034b9c1e341a6d88a6a81121858e99024967768df3c73507dd3ac31b' 
  AND token = 'aJWtxV5FNJXIRmwvKFSsfsk9fUzjXb5T1VKwrwwkTKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}