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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db27d876f2ded82b70fd4d61aef27885757d770d4b023ed521434d35b31d78d3' 
  AND token = 'XYDpb1XUd9EYih0D9HtQVbyBYj/mbTcPyFQPt8XKkqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}