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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c397c3e196e72ec929be149c09f684df9b380dd27f2ea7d2e7a025882282ff08' 
  AND token = 'hmJqJsEE8tn34jAGEYTAVb9pVJ8+5QZKZECN7UoGZ5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}