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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe47ffcc52fb7c83cfba085372aa222eaefc02613b230d5e2dc5bd7b12f7ace' 
  AND token = 'nVufTRBDhnC125MIsSlZ3RoqfkaPk+7Wxlzk8L+bc6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}