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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '734e9947e063017a4b58dbcfa36c3600996f3de51377e58d7078e6e9e7b904c2' 
  AND token = 'p1arnyOWhmfzXtWH3tv6DhaC2T6jR7dk4Ro4Wkp7dms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}