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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83cc8e9c78060b3aa78a2f4e65ed8b3edcc675f55e301f23c3d63f2d53d0accb' 
  AND token = 'ErY7fizSzClEbo43v95UPrWBN438QvmmSNYX12ClRp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}