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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a6ae22a288ea145034273f8659d2f7398bcdefc9b01c55081e189cbcc3591af' 
  AND token = '65p85rPHhgb88ZXHx/9uefGuXhNUs+ehIFC+NGTEd2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}