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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7abdf2de226958b14d07f2a7f31680e9fe1d2215dc756e2a95f6560010ec0981' 
  AND token = 'Euh18SGsxjzUuXWMRHXWH92w49Mpui67Y9fjYfnC2vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}