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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fe6801bb70626f634dfb616782b03aa1e8d8dc5759c161d3ddfe5bc8dbefdcc' 
  AND token = '8UybS2Kj80cSc9/key3LgXeEpqn6aB8LN3Trve/NoUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}