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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '407cc8ed7ef3abc22ad8013548aec688fd8bffa42bdc586ee29566226ba84227' 
  AND token = 'IUcIji3uUKP9zeNpNo0++tw47BnQwfUV1gpl/2ldMoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}