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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09ffe5657e4059e6c65a19665c99c65dbe84f6dd1b5c1e293c668c64ea400c25' 
  AND token = 'aoS8Jowqw5/wbMkF5LtPHyxVNSXr2xVSSeUn7Tn00uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}