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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f25e067ac61ab0c5a27ed67a09cac1f89f1f8e1b77b16f302704bcd2ff04bb' 
  AND token = 'O04eM+s3n0gOQZSjD6G0IdIzd/hNqRLbABCGxO0S/SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}