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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76f8ea3d5f2159d3455eeb567115c5fcba2d3216fbf8e74a3ef143742d75dbf8' 
  AND token = 'Z0AAw4yM2e7o9i8/3iY11cz8Qs2xuuSbRerAzphvdtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}