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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c2a7d57311228ddb6d5eb037b66ffee11c3674d8fa95b5d4f1d9f6b0502c117' 
  AND token = 'IMZBWsfZrgfhX8hPQl2yscIJYioVv4cK1Vt2bGthDHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}